Search for MethyMarks overlapped with super-enhancers
Recent studies have demonstrated that “Super-enhancer” is the large cluster of transcriptional enhancers that drive expression of genes that define cell identity (
Hnisz et al. 2013). We found cell-type-specific HypoMarks may be potential marks for cell-type-specific super-enhancers. For each cell-type, the MethyMarks overlapped with the super-enhancers from the same cell-type were identified and treated as Super-MethyMarks for the cell-type, including Super-HypoMarks and Super-HyperMarks. Here, we presented an atlas of Super-MethyMarks across 22 cell-types of human. Using the following Super-MethyMark selector, you can obtain the MethyMarks overlapped with super-enhancer in the given genome regions and cell-line or tissue. Other detailed parameters such as length, MethySpecificity, RefSeqID, GeneSymbol, CGILoc and Location would be useful for more precise search of elements of interest. DisplayRows can be set to show specific rows of results. The default search region (chr6:31124000-31147000) is around the well-known hESC markers POU5F1 (also known as OCT4).